Insecticide resistance has been an issue in north American for over 100 years. Insecticide use has fluctuated across time, but modern chemistries and genetically modified crops have contributed to a reduction in overall synthetic insecticide use in some areas. The use of insecticides has led some insects to become resistant. Resistance to insecticides continues to be a concern for agricultural production across North America. Insect resistance management has shown some ability to decrease or slow the development of resistance. There has been no indication that development of resistance will stop, even as technology has advanced and more than 50 years of resistance management research. Because of this, the trends that we have been seeing since the implantation of transgenic insecticidal crops will likely continue until the development of new chemistries and modes of action.