Sorghum is an important cereal, especially in the developing world where it is a major food source in regions where other cereal crops would not withstand the harsh conditions. After summarising sorghum’s nutritional status and world production figures, this chapter presents post-harvest operations: harvesting, transport, threshing, drying, cleaning, packaging and storage, then dehulling and milling. Means of storage and their management, major pests and their control as well as toxins produced by fungi are discussed. The chapter then lists the major transformations of sorghum and their end products. It then concludes with quality requirements.