Organic greenhouse tomato cultivation is expanding rapidly to meet consumer demand. This production system endeavours to minimize system inputs and adverse environmental impacts through sustainable water and waste management, limited fossil energy use, nutrient-balanced approaches, and mechanical and biological control of pests. Although organic greenhouse farming offers significant environmental and social benefits, it relies heavily on off-farm inputs, which seem to run counter to the principles of organic farming. This chapter shows how organic greenhouse tomato production can exceed local regulatory requirements and be seen as an innovative system aimed at achieving global food and ecosystem security through scientific and socioeconomic advances, policies, producer and stakeholder ingenuity, and public engagement.