This chapter focuses on breeding barley for durable resistance to net and spot forms of net blotch. It starts by reviewing how Pyrenophora teres f. teres can cause net form net blotch. The chapter then goes on to examine the molecular markers that can be identified to provide resistances to net form net blotch. A section on the population dynamics of barley–P. teres f. teres interactions is also provided. The chapter also reviews how breeding crops with specific genes can help to create durable resistance to net form blotch. It moves on to discuss how Pyrenophora teres Drechs. f. maculata can cause spot form net blotch and how identifying specific molecular markers can help provide resistance to this form of net blotch. The chapter concludes by highlighting the importance of combining durable resistance to both forms of net blotch.