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Assessing pyrrolizidine alkaloids in food
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31 January 2026

Food control of pyrrolizidine alkaloids (PAs) is currently in the spotlight of human health risk assessment due to their widespread presence in our daily diet. Within the last years, food alerts about concerning levels of these alkaloids in food have notably increased, due in part to improvements in their control. The EU regulation of PAs in certain foods is quite recent and has already undergone several updates. Therefore, increasing progress in the assessment of these compounds is needed to ensure food safety and comply with regulatory requirements. This chapter provides a comprehensive overview of PAs, including their contamination pathways, current regulation and evolution of their food alerts, highlighting the main contaminated products as far as they are currently known. Likewise, it gathers relevant analytical strategies for the assessment of PAs in food (2018-2024). Information about how food processing can influence the content and stability of these alkaloids is also included.
TECHNOLOGY & ENGINEERING / Food Science / Food Safety & Security, TECHNOLOGY & ENGINEERING / Agriculture / Sustainable Agriculture
- 1 Introduction
- 2 Contamination pathways for pyrrolizidine alkaloidsin food
- 3 Regulations governing pyrrolizidine alkaloid levelsin food
- 4 Assessing levels of contamination of food withpyrrolizidine alkaloids
- 5 Analytical methods for the assessment ofpyrrolizidine alkaloids in food
- 6 Stability and degradation products of pyrrolizidinealkaloids in food processing
- 7 Conclusion and future trends
- 8 References