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Windows to the Brain is the only book to synthesize neuroanatomical and imaging research as it pertains to selected neuropsychiatric diseases, containing all of the "Windows to the Brain" papers published from 1999-2006 in the Journal of Neuropsychiatry and Clinical Neurosciences. These reader-friendly summaries by more than sixty contributors present modern imaging techniques that assist in the diagnosis of neuropsychiatric illness, enhanced by easily understood color graphics of the neuroanatomical circuits of behavior, memory, and emotion. They provide a basic understanding of how to apply a variety of imaging techniques to the study of adult neuropsychiatric disease and how to use neuroimaging to assist in diagnostic work-ups for conditions ranging from sleep disorders to epilepsy to borderline personality.
Integrated,
color-coded graphics present functional anatomical information in a manner
that promotes understanding and use in clinical practice, while the text
encompasses a wide range of diseases and injuries across the adult lifespan.
The book is organized into four sections that will help readers increase
their appreciation of the wide range of research and clinical applications
for imaging in neuropsychiatry: chapters on imaging techniques discuss
underlying principles, strengths and weaknesses, and applications; chapters
on specific diseases demonstrate a range of investigative techniques;
anatomy/circuit chapters focus on particular brain structures or functional
neuropsychiatric circuits; and final chapters present image-based approaches
to understanding or selecting treatment options. Some of the applications
described are:
• Use of fMRI in posttraumatic stress disorder to reveal the delicate
balance between the structures of the emotion and memory tracks;
• Use
of high-resolution MRI and nuclear imaging to distinguish between panic
disorder and simple partial seizure disorder;
• Use of functional
imaging studies to detect corticobasal degeneration, as a means of better
understanding dementia;
• Use of newer imaging techniques in identifying
progressive multifocal leukoencephalopathy, to enable more rapid and
reliable tailoring of individual therapy for HIV;
• Use of functional
neuroimaging in the study of fear, in order to better understand and treat
anxiety-based psychiatric disorders;
• Use of neuroimaging studies in
conversion disorder, showing implications for the disruption of selfhood in
dissociative identity disorder and schizophrenia;
• Use of FDG-PET scans
to look for predictors of treatment response in childhood-onset
obsessive-compulsive disorder.
Windows to the Brain can help bring less-experienced readers up
to speed on advanced imaging and anatomical details that pertain to the
modern practice of neuropsychiatry. It is must-reading for specialists in
neuropsychiatry and cognitive/behavioral neurology, or for general
psychiatrists with an interest in neuroimaging.
This is an outstanding book, taken from the "Windows to the Brain" series from the Journal of Neuropsychiatry and Clinical Neurosciences. No neuropsychiatrist should be without a copy.
This book is a" must have" collection of 32 chapters, each only 5 to 10 pages long, packed full if numerous colorful imaging that bring light different imaging techniques used ti answer specific questions related to understanding the pathophysiology, diagnostic specificity, and treatment of various neuropsychiatric disorders.
Robin A. Hurley, M.D., is Associate Chief of Staff at the W.G. "Bill" Hefner VAMC in Salisbury, North Carolina, and Associate Professor in the Departments of Psychiatry and Radiology at Wake Forest University School of Medicine, Winston–Salem, North Carolina and Baylor College of Medicine in Houston, Texas.
Katherine H. Taber, Ph.D., is a Research Health Scientist at the W.G. "Bill" Hefner VAMC in Salisbury, North Carolina, and Research Professor in the Division of Biomedical Sciences at the Edward Via Virginia College of Osteopathic Medicine in Blacksburg, Virginia.
Contributors
Foreword
Preface
Part 1:
Imaging Techniques
Chapter 1. Blood Flow Imaging of the Brain:
50 Years' Experience
Chapter 2. Functional Magnetic Resonance Imaging:
Application to Posttraumatic Stress Disorder
Chapter 3. Ecstasy in the
Brain: A Model for Neuroimaging
Chapter 4. The Future for Diffusion
Tensor Imaging in Neuropsychiatry
Chapter 5. Cortical inhibition in
Alcohol Dependence
Chapter 6. Application of Magnetoencephalography to
the Study of Autism
Chapter 7. Applications of Xenon Computed tomography
in Clinical Practice: Detection of Hidden Lesions
Chapter 8. New
Techniques for Understanding Huntington's Disease
Part 2: Specific
Diseases
Chapter 9. Sudden Onset Panic: Epileptic Aura or Panic
Disorder?
Chapter 10. Bipolar Disorder: Imaging State Versus
Trait
Chapter 11. Blast-Related Traumatic Brain injury: What Is
Known?
Chapter 12. Mild Traumatic Brain injury: Neuroimaging of
Sports-Related Concussion
Chapter 13. Traumatic Axonal injury: Novel
insights into Evolution and Identification
Chapter 14. Functional
Imaging as a Window to Dementia: Corticobasal Degeneration
Chapter 15.
Metachromatic Leukodystrophy: A Model for the Study of Psychosis
Chapter
16. Identification of HIV-associated Progressive Multifocal
Leukoencephalopathy: Magnetic Resonance Imaging and Spectroscopy
Chapter
17. The Expanding Role of Imaging in Prion Disease
Chapter 18.
Applications of Functional Imaging to Carbon Monoxide Poisoning
Chapter
19. Binswanger's Disease: An Ongoing Controversy
Chapter 20. Normal
Pressure Hydrocephalus: Significance of Magnetic Resonance Imaging in a
Potentially Treatable Dementia
Chapter 21. Neuropsychiatric Presentation
of Multiple Sclerosis
Part 3: Anatomy and Circuitry
Chapter
22. Functional Neuroanatomy of Sleep and Sleep Deprivation
Chapter 23.
Neural Underpinnings of Fear and Its Modulation: Implications for Anxiety
Disorders
Chapter 24. Rabies and the Cerebellum: New Methods for Tracing
Circuits in the Brain
Chapter 25. Conversion Hysteria: Lessons From
Functional Imaging
Chapter 26. The Limbic Thalamus
Chapter 27.
Understanding Emotion Regulation in Borderline Personality Disorder:
Contributions of Neuroimaging
Chapter 28. Functional Anatomy of Central
Pain
Chapter 29. An Update on Estrogen: Higher Cognitive Function,
Receptor Mapping, Neurotrophic Effects
Part 4:
Treatment
Chapter 30. Predicting Treatment Response in
Obsessive-Compulsive Disorder
Chapter 31. Schizophrenia: What's Under
the Microscope?
Chapter 32. Surgical Treatment of Mental Illness: Impact
of Imaging
index