There has been a huge increase in the productivity of dairy cows over the last half a century, with the yield per cow more than doubling. This is substantially due to the use of genetic selection in dairy cattle breeding programmes. In this chapter, we review the use of artificial insemination (AI), progeny testing, embryo transfer and in vitro fertilization in breeding programmes. We then discuss how traditional progeny testing schemes are being replaced by genomic testing, resulting in a halving of the generation interval and a doubling of the rate of genetic gain. Finally, we review the objectives of breeding programmes, noting the move from focusing exclusively on production traits to an emphasis on other traits such as those related to health, fertility, functionality and feed efficiency.