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This book provides a detailed overview of cancer theranostics applications of magnetic iron oxide nanoparticles. Their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity are highlighted, along with current examples of clinical trials of magnetic nanoparticles in cancer theranostics, and their future scopes and challenges.
Table of Contents
Chapter 1: Introduction
1.1. Cancer and statistics
1.2. Conventional therapies for cancer and their limitations
1.3. Alternative theranostics strategy: Nanomedicine
1.4. Magnetic nanoparticles and cancer theranostics
Chapter 2: Magnetic nanoparticles: Types, synthesis and characterization
2.1 Common types of magnetic nanomaterials and their synthesis
2.2 Characterization techniques
2.3 Multilayer concept
Chapter 3: Magnetic nanoparticles for cancer diagnostics
3.1. MRI
3.2. Multimodal imaging
3.3. Biosensors
3.4. Cell labeling
Chapter 4: Magnetic nanoparticles for cancer therapeutics
4.1. Drug delivery: Chemotherapeutics, Biotherapeutics and Radiotherapeutics
4.2. Magnetic Hyperthermia
4.3. Photodynamic therapy
4.4. Photothermal ablation
4.5. MNPs as Anticancer agent
4.6. MNPs in Cancer Immunotherapy
Chapter 5: Safety of Magnetic nanomaterials, Challenges, future scope and Conclusion
5.1. Pharmacokinetics, biodistribution, toxicity
5.2. Targeting
5.3. Magnetic nanoparticles as FDA approved or in clinical trials
5.4. Challenges, future scopes and conclusion