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In order to increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The underlying physical principles of these oncological processes are a major constituent of the research field highlighted in Physics of Cancer.
This completely revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
Preface
About the author
Introduction
1 Initiation of a neoplasm or tumor
2 Inflammation and cancer
3 Cellular stiffness and deformability
4 Cell–cell and cell–matrix adhesion strength, local cell stiffness and forces
5 Cell surface tension, the mobility of cell surface receptors and their location in specific regions
6 Cytoskeletal remodeling dynamics
7 Actin filaments during matrix invasion
8 Intermediate filaments during matrix invasion