This chapter is focused on the North American subregion of Northern America, comprising the United States and Canada, which collectively represent 10% of global and 83% of North American agricultural land. Both nations rank among the top five global exporters of agricultural goods, playing a critical role in stabilizing global food markets, reducing price volatility, and enhancing food security. The chapter examines the projected impacts of shifting climate patterns driven by global climate change on agricultural systems in the region, including the potential effects on yields and yield stability. Additionally, it analyzes how the increasingly intensified, fossil fuel dependent agricultural sectors of the US and Canada contribute to global climate change. Finally, the chapter evaluates geographically tailored greenhouse gas mitigation strategies such as soil organic carbon sequestration, improved livestock management, and enhanced nitrogen management as well as region-specific adaptation measures, including the potential for northward agricultural expansion.