Agri-food scholars have long documented the deep-rooted social, cultural, and political issues that plague global agricultural systems. Still, there is a noticeable lack of empirical research examining the intersections of gender and race and their profound impact on individuals' lived experiences within agricultural spaces. This chapter reviews the key issues and challenges to navigating the intersections of gender, race, and agriculture on a global scale. The chapter describes the necessity of intersectional scholarship in contemporary agri-food systems research and considers the five significant challenges related to the intersection of gender and race in agriculture identified within academic literature. After providing insight from a case study of women agriculturalists working in Pittsburgh, Pennsylvania, the chapter calls for agricultural researchers, practitioners, and educators to reckon and engage with questions of intersectionality concerning agri-food systems work.