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Provides psychiatrists, oncologists, endocrinologists, pediatricians, and other health professionals with a thorough examination of the most current research on the role of melatonin in psychiatric and neoplastic disorders. This unique textbook and clinical reference is divided into four sections:
• Evolutionary Development and Neurobiology of the Pineal Gland—discusses the synthesis of melatonin and the anatomy of the pineal gland
• Melatonin in Psychiatric Disorders in Adults—pioneers in the field of pineology outline their findings on melatonin in the areas of adult depression, sleep disorders, chronobiological mood disorders, bipolar disorders, eating disorders, panic disorders, shift work maladaptation, and jet lag.
• Melatonin in Children and Adolescents—examines the pineal gland and melatonin in healthy children and adolescents and reviews recent studies on serum and urine melatonin in major depression
• Melatonin and Neoplastic Disorders—examines melatonin's potential as an antioxidant in cancer cells and its diagnostic and therapeutic value in oncology
The final chapter looks at the role that mindful meditation plays in increasing nocturnal serum melatonin and examines meditation's potential as an adjunct treatment for breast, prostate, and gastrointestinal tract cancers or as a preventive measure for high-risk individuals.
With the expert knowledge and current research presented in Melatonin in Psychiatric and Neoplastic Disorders, clinicians can provide accurate information to their patients on melatonin's role in health and disease.
Psychiatric readers will most benefit from the excellent chapters on the role of circadian rhythms and melatonin production in patient with mood disorders. This is the area—not, as is widely held by the public, in the treatment of primary insomnia—that currently has the strongest theoretical support for a role of melatonin in the pathophysiology and treatment of psychiatric disorders. . . each chapter is superb. . . psychiatric practitioners trying to update themselves on the scientific support for the use of melatonin in psychiatric disorders and for its appropriate use by the public will find this book an informative addition to their library.
— American Journal of Psychiatry
Mohammad Shafii, M.D., is Professor of Psychiatry and Director of the Child and Adolescent Psychiatry Residency Training Program in the Department of Psychiatry and Behavioral Sciences at University of Louisville School of Medicine in Louisville, Kentucky.
Sharon L. Shafii, R.N., B.S.N., is Editor-in-Residence in Louisville, Kentucky. Ms. Shafii was formerly Assistant Head Nurse in the Adolescent Service at the Neuropsychiatric Institute, University of Michigan Medical Center, in Ann Arbor, Michigan.
Evolutionary Development and Neurobiology of the Pineal Gland. Changes in melatonin throughout the life cycle: implications for neurobiology and psychiatry. The structure and evolutionary development of the pineal gland. Melatonin in Psychiatric Disorders in Adults. Melatonin in adult depression. Melatonin in circadian phase sleep and mood disorders. Melatonin and circadian rhythms in bipolar mood disorders. Melatonin in eating and panic disorders. Melatonin in Children and Adolescents. Melatonin in nondepressed and depressed children and adolescents. Melatonin in sleep disorders in children with neurodevelopmental disabilities. Melatonin and Neoplastic Disorders. Melatonin at the neoplastic cellular level. The melatonin rhythm in cancer patients. Meditation, melatonin, and cancer. Index.