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Sepsis is a life threatening reaction to an infection. It happens when the body’s immune system overreacts to an infection and starts to damage its own tissues and organs.
This handbook provides up-to-date strategies in sepsis management for physicians, surgeons, anaesthetists and critical care trainees.
The book caters to the need for understanding sepsis evolution, from initial presentation, various early diagnosis techniques and imaging, to organ dysfunction, management aspects and future therapies.
Comprising six sections and 23 chapters, the comprehensive text is authored by an experienced multidisciplinary team specialising in the fields of infectious diseases, microbiology and critical care medicine.
Kapil Gangadhar Zirpe MBBS MD (Chest) FICCM FCCM FSNCC
Head and Director, Neurotrauma Intensive Care Unit, Grant Medical Foundation, Ruby Hall Clinic, Pune, Maharashtra, India
Subhal Bhalchandra Dixit MD IDCCM FICCM FICP FCCM
Consultant (Critical Care) and Director (ICU), Department of Critical Care, Sanjeevan and MJM Hospitals, Pune, Maharashtra, India
Yatin Mehta MD MNAMS FRCA FAMS FIACTA FICCM FTEE
Chairman, Medanta Institute of Critical Care and Anaesthesiology, Medanta - The Medicity, Gurugram, Haryana, India
Subhash Todi MD MRCP
Director, Department of Critical Care, Manipal Hospitals, Kolkata, West Bengal, India
SECTION 1: Introductory Chapters
1. Applied Pathophysiology of Sepsis
2. Evolution of Sepsis: Concept and Definition
3. Epidemiology of Sepsis
SECTION 2: Initial Presentation
4. Initial Evaluation of Sepsis
5. Initial Resuscitation of Sepsis
6. Identifying and Controlling the Source of Sepsis
7. Identifying Sepsis Mimics
8. Identifying and Managing Severe Tropical Sepsis
SECTION 3: Diagnostics
9. Conventional Blood Culture: Why and How?
10. Role of Rapid Molecular Diagnostics
11. Biomarkers in Sepsis
12. Role of Imaging in Sepsis
SECTION 4: Organ Dysfunction and Support
13. Renal Failure in Sepsis
14. Septic Encephalopathy
15. Septic Coagulopathy
16. Liver/Gut Dysfunction and Nutritional Support in Sepsis
17. Sepsis-Induced Cardiomyopathy
18. Endocrine Dysfunction and Role of Steroids in Sepsis
SECTION 5: Antimicrobials in Sepsis
19. Managing Multidrug-Resistant Gram-Negative Infection
20. Gram-Positive Bacteremia: A Review
21. Appropriate Use of Antifungals
22. Infections in Immunocompromised Host
SECTION 6: Adjunctive Therapies in Sepsis
23. Adjunctive Therapies in Sepsis