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Cognitive Behavioral Therapy for Insomnia in the Context of Comorbid Mental Health Conditions
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07 March 2026
An estimated 6%–10% of the U.S. population meets the criteria for insomnia disorder—a figure that is even higher among individuals experiencing psychiatric conditions. Evidence suggests that although experiencing sleep difficulties is a diagnostic criterion in several psychiatric conditions and is experienced in the context of some medical disorders, insomnia is a distinct disorder, intricately interwoven with co-occurring medical and psychiatric conditions.
This insightful new book explores Cognitive Behavioral Therapy for Insomnia (CBT-I) in a manner relevant to patients seen by mental health clinicians. CBT-I is an effective nonpharmacological treatment approach grounded in the sciences of sleep and behavior change. The volume's distinguished contributors carefully consider the components of CBT-I and provide guidance on customizing treatment for patients with and without co-occurring psychiatric conditions.
After an initial review of the etiology, pathophysiology, and diagnostic features of insomnia, the authors explore a range of topics, including the following:
• Evidence supporting the efficacy of CBT-I and its components
• Pharmacological approaches and strategies for tapering patients off hypnotic medications while they undergo CBT-I
• Applying CBT-I in the context of specific psychiatric disorders such as ADHD, depression, schizophrenia, bipolar disorder, and substance use
• Adapting CBT-I for unique patient populations, including adolescents, pregnant patients, and older adults
• Cultural considerations for treating insomnia in Black, Hispanic, and Asian patients
Case examples, detailed tables, and key points illustrate the application of CBT-I principles.
Insomnia is not only debilitating and life-altering for those affected; it also carries significant economic and public health consequences. Cognitive Behavioral Therapy for Insomnia in the Context of Comorbid Mental Health Conditions provides clinicians with the knowledge and tools to offer meaningful relief to their patients.
MEDICAL / Psychiatry / General
Andrea Goldstein-Piekarski, Ph.D., is Assistant Professor, Department of Psychiatry and Behavioral Sciences, at Stanford University School of Medicine in Stanford, California, and Investigator, Mental Illness Research Education and Clinical Center, at the VA Palo Alto Health Care System in Palo Alto, California.
Rachel Manber, Ph.D., is Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology–Adult), Department of Psychiatry; Director of Stanford's Sleep Health and Insomnia Program; and Co-director of the multidisciplinary Center for Sleep and Circadian Rhythms at Stanford University in Stanford, California.
Section 1. Insomnia General Introduction
Chapter 1. Insomnia Diagnosis, Etiology/Pathophysiology and Subtyping
Chapter 2. Assessment of Insomnia in the Context of Comorbid Mental Health Disorders
Section 2. Cognitive Behavioral Therapy for Insomnia (CBT-I) General Introduction
Chapter 3. Cognitive Behavioral Therapy for Insomnia: Overview and Efficacy
Chapter 4. Impact of CBT-I on Physiological Measurements of Sleep and Arousal Systems in Insomnia Disorder
Chapter 5. Behavioral Components of CBT-I: Sleep Restriction Therapy, Stimulus Control, and Sleep Hygiene
Chapter 6. Cognitive Components of CBT-I
Chapter 7. Integrating Acceptance- and Mindfulness-Based Strategies into CBT-I
Chapter 8. Addressing Sleepiness and Fatigue in CBT-I
Chapter 9. Targeting Circadian Factors in CBT-I
Chapter 10. Putting Together the Components of CBT-I: Using a Flexible Approach
Section 3. Pharmacotherapy for Insomnia Among Individuals with Psychiatric Comorbidities
Chapter 11. Pharmacotherapy of Insomnia in Adults
Chapter 12. Integrating Hypnotic Tapers into CBT-I
Section 4. Insomnia Presentations and Implementation of CBT-I/Behavioral Interventions in Common Comorbid Psychiatric Disorders
Chapter 13. CBT-I in Patients with ADHD
Chapter 14. CBT-I in Patients with Schizophrenia and Psychosis
Chapter 15. CBT-I in Patients with Bipolar and Related Disorders
Chapter 16. CBT-I in Patients with Depressive Disorders
Chapter 17. CBT-I in Patients with Anxiety Disorders
Chapter 18. CBT-I in Patients with PTSD
Chapter 19. CBT-I in Patients with Substance Use Disorders
Section 5. Considerations for Other Specialized Populations
Chapter 20. CBT-I in Adolescents
Chapter 21. CBT-I in Pregnancy & Postpartum
Chapter 22. CBT-I in Older Adults
Chapter 23. CBT-I in Comorbid Medical Conditions
Chapter 24. Sociocultural Factors in the Phenomenology and Treatment of Insomnia in Black, Hispanic, and Asian Adults in the United States of America