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In recent years, pig genetics and breeding has been revolutionized by advances in genomics. This chapter outlines current developments in pig genetics and genomics including long-read sequencing, telomere-to-telomere assembly, low-pass sequencing for genomic prediction, functional genomics, fine-mapping quantitative trait loci (QTL), and identification of deleterious alleles. The increases in functional genomic data and information on gene expression are currently providing a much more detailed insight into the genotype-phenotype relationship for complex traits and the molecular pathways involved. Fine-mapping of causal variants will become feasible with the use and availability of these types of data in different tissues and timepoints, and will provide a gateway to assess the influence of regulatory variation in the pig genome.
- 1 Introduction
- 2 Developments in pig genomics
- 3 Genomic selection and quantitative trait loci mapping
- 4 The functional genome and causal variation
- 5 Case study: quantitative trait loci fine-mapping for meat quality traits identifies genes involved in muscle glycogen storage
- 6 Mapping of deleterious variation
- 7 Conclusion and future trends
- 8 Where to look for further inforamtion
- 9 References