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Advances in Treatment of Bipolar Disorder
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17 June 2005

Despite works published as recently as 2002, the continuing rapid evolution of new medications and adjunctive psychosocial interventions for bipolar disorder has made the concise Advances in Treatment of Bipolar Disorder essential for today's clinicians who want to stay abreast of the latest developments in treating this complex and challenging mental illness.
Meticulously referenced with numerous tables and
illustrations, Advances in Treatment of Bipolar Disorder offers a
very timely and exciting perspective on new ways to treat bipolar disorder.
After an overview, six succinct chapters written by experts review recent
developments—emphasizing interventions supported by controlled studies—in
the following areas:
• Advances in treatment of patients with acute mania: discussing
newer antipsychotics, which as a class are effective as primary treatments
for acute mania, and have emerging potential roles in maintenance treatment,
and acute bipolar depression; and anticonvulsants, some of which are
effective for as primary treatments for acute mania or maintenance, and
others of which although not primary treatments for bipolar disorders may
provide benefits as adjuncts for comorbid conditions.
• New
developments in the treatment of acute bipolar depression:
describing therapeutic options beyond mood stabilizers and highlighting that
adjunctive use of antidepressants requires additional adequately powered
controlled studies to support this common approach.
• Techniques in
the maintenance treatment of patients with bipolar disorder:
including both medications and adjunctive psychosocial therapies, which
together can help clinicians manage medication adverse effects and maintain
the therapeutic alliance, treatment adherence, and involvement of
significant others to enhance outcomes.
• Innovations in the
treatment of rapid-cycling bipolar disorder: although no treatment
has received FDA approval for the management of this challenging
presentation, results of controlled trials are beginning to provide
clinically relevant insights in to the treatment of patients with rapid
cycling, offering hope for more effective future therapies.
• The
treatment of children and adolescents with bipolar disorder: no
treatment has FDA approval for the treatment of pediatric patients with
bipolar disorder and controlled data are limited, yet recent research is
beginning to yield important new information about the diagnosis and
management of children and adolescents with this illness or its putative
prodromes.
• Phenomenology and management of bipolar disorder in
women: introducing important new information to enhance clinicians'
understanding of the importance of accounting for gender differences and
reproductive health in the treatment of women with bipolar disorder.
Advances in Treatment of Bipolar Disorder helps clinicians to better understand the utility of both older medications and important new treatment options as it highlights the need for additional research to ensure further progress in overcoming the challenges of caring for patients with bipolar disorder.
MEDICAL / Psychiatry / General
Terence A. Ketter, M.D., is Professor of Psychiatry and Behavioral Sciences and Chief of the Bipolar Disorders Clinic at Stanford University School of Medicine in Stanford, California.
Contributors
Introduction to the Review of Psychiatry
Series
Chapter 1. Introduction
Chapter 2. Treatment of Acute Mania
in Bipolar Disorder
Chapter 3. Treatment of Acute Depression in Bipolar
Disorder
Chapter 4. Long-Term Management of Bipolar Disorder
Chapter
5. Treatment of Rapid-Cycling Bipolar Disorder
Chapter 6. Treatment of
Children and Adolescents With Bipolar Disorder
Chapter 7. Special
Considerations for Women With Bipolar Disorder
Index