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Point-of-care testing devices for early detection, screening and diagnosis have been proven to significantly improve patient survival rates and quality of life, as well as to significantly reduce the cost and complexity of disease treatment. Providing a timely update on the current understanding of paper-based biosensors, this book aims to deal with the current state-of-the-art of paper-based biosensors technology and addresses its future prospects for the detection of infectious diseases, with particular relevance and applications for low-income and developing countries. This book focuses on the design and fabrication strategies of paper-based devices for the detection of various biomolecules in biomedicine. This comprehensive research and reference text would be suitable for researchers, scholars, and manufacturers in multiple disciplines, such as medical device design.
Key Features
- Highlights the fabrication of paper-based point-of-care devices for biomedical applications with a particular focus on low-income and developing countries
- Covers the approaches to design novel, cost-effective paper-based devices for disease diagnosis
- Includes information on tags/probes/label-based and label-free paper-based devices
- Discusses the integration of paper-based techniques and advanced diagnostics
- Contains actual case studies of the fabrication and utilisation of paper-based diagnostics in the field in each chapter
1 Paper-based biosensors: overview from past to future
2 Paper-based biosensor as an early diagnostic system in medical sciences
3 Fabrication of paper-based immunochromatography assay
4 Fabrication of surface-enhanced Raman scattering based lateral flow assay for disease diagnosis
5 Design and fabrication of tag/probe-based and label-free paper-based devices
6 Development of aptamer-based lateral flow assays
7 Paper-based diagnostics for SARS-CoV-2
8 Development of paper-based assay for detection of miRNA in various diseases
9 PCR and other nucleic acid amplification technique based lateral flow assay for detection of the infectious agents
10 Plasmonic thermal based lateral flow assay for detection and quantification of antibody/antigen
11 State-of-the-art of paper-based technology and challenges in its commercialization
12 Sensing technologies used in microfluidic paper-based analytical devices (μPADs)
13 Integration of paper-based analytical tools with smartphones and IOMT
14 The futuristic paradigm shift in the field of biosensing applications