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Cytogenetics is the study of the structure and function of the cell, particularly chromosomes.
Manual of Cytogenetics in Reproductive Biology examines the diagnostic role of cytogenetics in improving the outcome of assisted reproductive technologies (ART).
Divided into six sections, the book begins with the basics of genetics, followed by investigative cytogenetics, applied cytogenetics, recent advances, preimplantation and prenatal cytogenetics.
This comprehensive guide includes nearly 200 clinical images, diagrams and tables, and is an invaluable reference for practising specialists in genetics, infertility and obstetrics and gynaecology.
Key points
- Examines diagnostic role of cytogenetics in improving outcome of ART
- Six sections each providing in depth coverage of different aspects of cytogenetics
- Includes nearly 200 clinical images, diagrams and tables
- Invaluable for specialists in genetics, infertility and OBSGY
Pankaj Talwar VSM
Professor and Head, Department of Obstetrics & Gynaecology, Assisted Reproductive Technologies Centre, INHS Asvini, Mumbai, Maharashtra, India
Section 1: Basics of Genetics and Genetics Laboratory
- Structure of DNA
- Chromosome Nomenclature and Cell Division
- Microscopes in Assisted Reproductive Technology
- The Cell Cycle and Cell Division
- Cell
Section 2: Investigative Cytogenetics
- Cytogenetics
- Polymerase Chain Reaction
- Human Chromatin
- Molecular Techniques in Preimplantation Genetic Diagnosis
Section 3: Applied Cytogenetics
- DNA Fragmentation and Pregnancy Loss
- Cytogenetics of Infertile Women
- Cloning
- Premature Ovarian Failure: A Chronic Debilitating Condition of Womanhood
- Genetics and Male Infertility
- Sperm DNA Damage Assessment: Techniques and Relevance in Male Infertility Diagnostics
- Patterns of Inheritance
- Epigenetics
- Inborn Errors of Metabolism
- Male Infertility and Cytogenetics
- Cytogenetics in Recurrent Miscarriages
- Chromosomal Polymorphic Variants and Reproductive Outcome
- Oocyte and Maternal Inheritance
Section 4: Cytogenetics: Recent Advances
- Cell Sorting in Genomics: Beginners’ Guide
- Gene Therapy
- Recombinant DNA Technology
- Blot Tests
- Whole Genome Amplification and CGH: Recent Molecular Biology Techniques in Cytogenetics
- Soluble Human Leukocyte Antigen-G: Embryology in the Era of Proteomics
- Role of Centrosome in Fertilization and Beyond in Assisted Reproduction
- Human Genome Project
Section 5: Preimplantation Cytogenetics
- Preimplantation Genetic Diagnosis: A Review
- Preimplantation Genetic Diagnosis in Assisted Reproductive Technology
Section 6: Prenatal Cytogenetics: Clinical Applications
- Prenatal Cytogenetics
- Prenatal Diagnosis of Down Syndrome and other Chromosomal Disorders and Counseling for Abnormal Serum Marker Analytes
- Common Genetic Syndromes in Clinical Practice
- Assisted Reproductive Technology and Genetic Counselling